The building in Via Panisperna has an exceptional historical value and, in order, to honor the memory of Enrico Fermi and his group of the “Boys of Via Panisperna” a museum was set up. This is dedicated to the scientific heritage of Fermi. Through the Museum CREF aims to offer a wide dissemination and communication of Fermi’s life and discoveries. The museum activity is complemented by different types of initiatives for the dissemination and dissemination of scientific culture to a wide and varied audience, with particular attention to schools and universities.